Revista de Dermatologia e Doenças Dermatológicas

A Neurocutaneous Syndrome Proceeding with Pigmentation Disorder: Neurofibromatosis Type 1

Abstract

Ragip Ismail Engin and Atilla Cayir

Neurofibromatosis type 1 is a relatively common inherited disease. The condition may involve frequently difficult to manage benign and malignant tumors in affected patients and can also affect tissues such as bone and skin. Symptoms include large numbers of cafe-au-lait macules, tumoral lesions known as neurofibromas, and scoliosis in the spinal cord. Tumors may also be seen in the brain, the cranial nerves or the spinal cord. This study discusses type 1 neurofibromatosis in the light of the current literature.