Vitaminas e Minerais

Vitamin D and Cognitive Function in Bipolar Disorder: A Comparative Study with Healthy Controls

Abstract

Tinkoo Serra*

This cross-sectional study explores the intricate relationship between vitamin D status and cognitive function in individuals diagnosed with bipolar disorder in comparison to healthy controls. We conducted comprehensive cognitive assessments alongside measurements of vitamin D levels in a cohort comprising 75 bipolar disorder patients and 75 age-matched healthy controls. The results reveal a striking correlation between lower vitamin D levels and compromised cognitive abilities, particularly in domains such as memory, attention and executive function among individuals with bipolar disorder. In contrast, the healthy control group exhibited higher vitamin D levels and superior cognitive performance. These findings underscore the potential significance of vitamin D supplementation as an adjunctive intervention to ameliorate cognitive impairments in bipolar disorder, emphasizing the need for further investigation and potential therapeutic applications.