Vitaminas e Minerais

Rescue of Islet β Cells from High Glucose-induced Apoptosis through Vitamin B12-induced Autophagy

Abstract

Hyuana Kim*

The survival and function of islet β cells are crucial for maintaining glucose homeostasis. High glucose levels can induce apoptosis in these cells, contributing to the pathogenesis of diabetes. This paper explores the protective effects of vitamin B12-induced autophagy as a mechanism to rescue islet β cells from high glucose-induced apoptosis. Through a comprehensive review of the literature and discussions on the potential implications of this phenomenon, we shed light on the promising role of vitamin B12 in preserving β cell integrity and function, offering new avenues for diabetes research and therapy.