Vitaminas e Minerais

Potential Anticancer Activity of Tocotrienols

Abstract

Sajid I, Majumder T, Arif MH and Alam Z

Natural compounds of plant origin are being used in cancer research since several decades. More than treatment, they hold promise in cancer prevention. Besides cancer, they are also used in other health disorders. Interest in natural compounds mediated treatment is increasing due to their low toxicity, wide variety of health benefits and natural abundance. They can be easily obtained from nature and can be taken in diet without doctor consulting based upon their availability. As they do not result in significant health problems, a little change in dietary habits can give us benefit against various diseases including cancer. Tocotrienols are vitamin E groups of compounds obtained from Pam oil in high concentrations. In this review, we describe the anticancer activities of Tocotrienols in various cancer types. Tocotrienols have shown potential in vitro and in vivo activity and are being tested in several clinical studies.