Vitaminas e Minerais

Metal-Ligand Homeostasis in Epidermic Cells of Chernobyl Accident Liquidators

Abstract

Petukhov VI, Dmitriev EV, Kalvinsh I, Baumane LKh, Reste ED, Zvagule T, Skesters AP and Skalny AV

The present article is an attempt to reveal the connection (Pearson) between potassium (K) and sodium (Na), K and zinc (Zn) levels on the basis of analytical determination of elemental content in human scalp hair (atomic emission spectrometry in 954 Chernobyl accident liquidators and 947 healthy persons). The negative K-Zn correlation and also the increase in epidermic cells K and Na and reduction of calcium (Ca) and Zn can indirectly point, in the authors opinion, to the participation of membrane АТРаs (P-type) in the origin of metal-ligand homeostasis shifts and serve as oxidative and nitrosative stress discriminators.