Jornal da Síndrome Metabólica

Galactorrhea without Hyperprolactinemia in a Male Patient with Acromegaly: A Case Report

Abstract

Yuki Kitada, Hidetoshi Ikeda and Kazuo Watanabe

There are numerous pathologic causes of galactorrhea. Hyperprolactinemia and hypothyroidism are frequently associated with galactorrhea as a result of hormonal imbalances. Patients with acromegaly sometimes have hyperprolactinemia, and some also have galactorrhea. Here, we report on a male patient with acromegaly who suffered from galactorrhea without hyperprolactinemia. This 42-year-old patient had a pituitary adenoma, but his serum hormone levels were within normal ranges, except for the growth hormone and insulin-like growth factor 1. Transsphenoidal surgery was performed and subsequent histopathologic studies confirmed it was a plurihormonal adenoma. After surgery, his GH and IGF-1 levels decreased to within the normal ranges, and his galactorrhea also disappeared. To the best of our knowledge, this is the first reported case of a male patient with acromegaly who suffered from galactorrhea without hyperprolactinemia.