Jornal de Biomarcadores Moleculares e Diagnóstico

Towards the Dreamed Biomarkers?

Abstract

Ranuncolo SM

Detection and determination of tumor biomarkers are made from tissue and blood collection. During the last decade new biological sources are feasible: circulating tumor cells and circulating nucleic acids. They are composing a new field named as liquid biopsy. The availability of next-generation sequencing and Digital-PCR among other techniques, led to the possibility of getting the most out of this “circulating material” that would mirror the genetic and epigenetic features of the tumor.