Jornal de Biomarcadores Moleculares e Diagnóstico

Ryanodine Receptor Mutation in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Clinical Implications

Abstract

Ashkan Ehdaie, Michael Shehata, Xun-Zhang Wang, Sumeet Chugh and Eugenio Cingolani

This is case of a 40-year-old otherwise healthy and physically active gentleman noted the onset of palpitations while running upstairs the day of admission to the emergency room. On arrival to the emergency room, his heart rate was noted to be 250 beats-per-minute (bpm) and electrocardiogram (ECG) demonstrated ventricular tachycardia (VT). Synchronized electrical cardioversion was performed to sinus bradycardia. He was stabilized and admitted to the hospital. There was demonstration of right ventricular VT with an inferior axis, T-wave inversions in the right precordial leads with a right bundle branch block (RBBB) pattern, epsilon waves, and bidirectional premature ventricular contractions (PVC).