Jornal de Biomarcadores Moleculares e Diagnóstico

Molecular Profiling of Axial Spondyloarthritis Patients: Unraveling Pathogenesis and Personalized Medicine Opportunities

Abstract

Ian Butts

Axial Spondyloarthritis (axSpA) is a chronic inflammatory condition primarily affecting the axial skeleton, characterized by inflammatory back pain, sacroiliitis and structural damage. Despite advancements in treatment options, there remains a significant unmet need for accurate diagnosis, prognosis and personalized therapeutic strategies. Molecular profiling techniques have emerged as powerful tools in understanding the pathogenesis of axSpA, elucidating molecular signatures associated with disease activity, severity and treatment response. This article provides a comprehensive overview of molecular profiling in axSpA patients, exploring its potential implications for precision medicine approaches.