Medicina Molecular e Genética

Alzheimer's disease, a progressive neurodegenerative disorder, poses a significant challenge to healthcare systems worldwide. With an aging population, the prevalence of Alzheimer's disease is on the rise, making it a growing public health concern. Precision medicine, an emerging approach in healthcare, aims to tailor medical care to individual characteristics, including genetic makeup. Genetic testing has played a pivotal role in the evolution of precision medicine for Alzheimer's disease patients. In this article, we will explore the history and evolution of genetic testing in the context of Alzheimer's disease, its current applications, challenges, and the promise it holds for personalized treatment and prevention. Alzheimer's disease is characterized by the progressive decline of cognitive function, including memory, thinking, and reasoning. It is the most common cause of dementia in older adults. The disease is complex, with both genetic and environmental factors contributing to its development.

Genomic medicine, the field that integrates genetics and genomics into medical practice, has experienced remarkable advancements in recent years. As this discipline becomes increasingly integrated into healthcare systems worldwide, various rhetorical approaches have emerged in discussing its significance and implications. In this article, we will explore the rhetoric surrounding genomic medicine from three distinct angles: as an exceptional breakthrough, as an ordinary aspect of modern medicine, and as an ethical obligation. Each perspective sheds light on different facets of genomic medicine's role in shaping the future of healthcare. One of the prevailing rhetorical narratives surrounding genomic medicine portrays it as an exceptional, paradigm-shifting breakthrough in the field of healthcare. In this view, genomics is positioned as the cornerstone of a new era in medicine, offering revolutionary insights and transformative capabilities. Here are some key arguments and considerations within this rhetoric.

Pediatric genomic medicine has revolutionized healthcare by providing insights into the genetic basis of diseases in children. In recent years, the use of genetic testing for ancestry information has become increasingly common in pediatric genomics. These tests can provide valuable insights into a child's genetic heritage and can be used to identify potential disease risks, inform treatment decisions, and facilitate better healthcare outcomes. However, the integration of genetic ancestry findings into pediatric genomic medicine also raises complex ethical, legal and social issues. In this article, we will explore the role of genetic ancestry findings in pediatric genomic medicine, its applications, benefits, and the associated ethical considerations. Genetic ancestry findings, often referred to as genetic ancestry testing or DNA ancestry testing, involve the analysis of an individual's DNA to determine their genetic heritage and ancestry.

Mitochondria, often referred of the cell, play a pivotal role in cellular energy production and various metabolic processes. These tiny organelles have their own genetic material, distinct from the nuclear genome, and are inherited exclusively from the mother. Mitochondrial genetic variation has garnered increasing attention in the context of precision medicine, a rapidly evolving field that tailors medical treatments and interventions to individual characteristics. In this article, we will explore the significance of mitochondrial genetic variation, its potential implications for precision medicine, current challenges, and the promising avenues for further research and characterization. Mitochondria are responsible for generating adenosine triphosphate the cell's primary energy currency. Mutations in mitochondrial DNA can disrupt this process, leading to various metabolic and energy-related disorders. Mitochondrial diseases are a group of rare genetic disorders caused by mutations in mtDNA.