Genética Humana e Embriologia

Next-Generation Sequencing (NGS) -The future of Genomic Medicine is here. Genomics -The Alexander who conquered the world!

Abstract

Manjeet Mehta

The Human Genome Project has given us information on the structure of human DNA and how the human genome functions. It has helped identify and isolate human genes, particularly those associated with disease; and has drastically altered our approach to medical care.

Medical professionals conventionally use diagnostics to select the appropriate treatment in almost 70% of their cases. Due to recent advances there has been an increase in the role of molecular genetics and genomics testing in the clinical diagnostics services.

Medical genomics is the speciality of applying and integrating genomic data, as well as information from functional genomics, the genome structure, population studies, epigenomics, proteomics, analysis of systems and pharmacogenomics, all this leading to a better understanding of the genetic bases of drug response and disease initiation & progression.

Genomic testing has brought in a new period in medicine, leading to a medical revolution which is purely evidence-based. Today the genotype gives information about not only the confirmed diagnosis, but even the classification, severity, prognosis, and the best treatment

Healthcare delivery is being transformed by clinical genomics, profoundly altering our approach to medical care, from one of treatment of advanced disease to prevention based on the identification of individual risk.