Jornal de Microbiologia e Patologia

Molecular Mechanisms of Drug Resistance in Pathogenic Bacteria

Abstract

Zahra Martins

The emergence and spread of antibiotic resistance among pathogenic bacteria pose a significant threat to global public health. Understanding the molecular mechanisms behind antibiotic resistance is crucial for the development of effective strategies to combat this problem. This article provides an overview of the key molecular mechanisms employed by pathogenic bacteria to evade the effects of antibiotics. It discusses the role of genetic mutations, horizontal gene transfer, efflux pumps, target site modification and biofilm formation in antibiotic resistance. By elucidating these mechanisms, researchers can identify potential targets for the development of novel antimicrobial agents and devise innovative strategies to prevent the spread of antibiotic resistance.