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Jornal de Ciência da Computação e Biologia de Sistemas

Volume 17, Emitir 1 (2024)

Mini revisão

Blockchain in Bioinformatics Enhancing Security and Transparency in Systems Biology Research

Angelo Jarman*

In the fast-evolving landscape of scientific research, particularly in the realm of systems biology, the need for robust data management and security has become increasingly crucial. Traditional methods of data storage and management have faced challenges related to security breaches, data integrity, and transparency. The integration of blockchain technology in bioinformatics offers a promising solution to address these concerns, providing a decentralized and secure framework for managing and sharing sensitive biological data. In this article, we delve into the intersection of blockchain and bioinformatics, exploring the potential benefits, challenges, and applications of blockchain in enhancing security and transparency in systems biology research.

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Computational Immunology Harnessing the Power of Algorithms to Decode the Immune System

Eduardo Gustavo*

In the realm of medical research, the intersection of biology and computer science has given rise to a groundbreaking field known as computational immunology. This burgeoning discipline seeks to unravel the complexities of the immune system using advanced algorithms and computational models. The immune system, an intricate network of cells and proteins, plays a crucial role in defending the body against pathogens and maintaining overall health. Computational immunology leverages the power of data analysis, mathematical modeling, and machine learning to decipher the intricacies of immune responses, paving the way for innovative approaches to understanding diseases and developing targeted therapeutic interventions.

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CRISPR and Code the Synergy of Gene Editing and Computational Advances in Systems Biology

Jorge Ferreira*

In the realm of modern biology, two groundbreaking fields, gene editing through CRISPR technology and computational systems biology, are converging to revolutionize our understanding of genetics and biological systems. This article explores the powerful synergy between CRISPR and code, highlighting how the integration of gene-editing techniques with computational approaches is reshaping the landscape of systems biology. CRISPR, or Clustered Regularly Interspaced Short Palindromic Repeats, was initially discovered as a part of the bacterial immune system. However, scientists have ingeniously adapted and repurposed this system into a revolutionary gene-editing tool. Concurrently, the field of systems biology has emerged as a holistic approach to studying the complex interactions within biological systems. The fusion of CRISPR and computational systems biology is transforming the way we explore and manipulate the fundamental building blocks of life.

Mini revisão

Challenges and Opportunities Integrating Computer Science Techniques in Systems Biology Research

Rafael Leindecker*

In the rapidly evolving landscape of biological research, the integration of computer science techniques into systems biology has emerged as a transformative force, offering novel insights into the complexities of living organisms. This synergy between computer science and biology holds the promise of unraveling intricate biological networks, predicting cellular behaviors, and accelerating drug discovery processes. However, this integration is not without its challenges. In this article, we explore the hurdles and opportunities associated with the convergence of computer science and systems biology, shedding light on the path ahead for researchers in these interdisciplinary fields.

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