Desenvolvimento e aplicações de biocerâmica

A year has passed since Bioceramics Development and Applications opened for submissions. Weâ??d like to take this opportunity to look back on the past year and thank all those who have contributed to the journal. For the editorial staff of Bioceramics Development and Applications, the year since we opened for submissions has passed in a blur.

On behalf of the editors of the Journal of Bioceramics Development and Applications, I would like to express my sincere gratitude to the reviewers for assessing manuscripts. The editors greatly appreciate the contribution of reviewers who have dedicated their valuable time and efforts in reviewing the assigned manuscripts, which is crucial to the journalâ??s editorial decision-making process. The Journal of Bioceramics Development and Applications follows a double-blind peer-review process, where the identities of both the authors and reviews are not disclosed, to avoid any biases.

The study of the microstructure reveals that several small pores (approximately 25-50 μm in diameter) were uniformly dispersed around the surface of the sample. The grains were flake-like, ranging from a diameter of 100 nm to 1 μm and a thickness of around 40 nm. The cement displayed a high injectability of > 90 percent by weight, and no apparent filter pressing was noted during ejection. The XRD study of dried samples found that a total of approximately 17 percent of unreacted β-TCP and β-CPP were still present in the cement, while all MCPM had reacted. Brushite was the predominant precipitated element, with approximately 5% wt of current monetite.

SEM images of both mineralizing (subclone 4) and nonmineralizing (subclone 24) MC3T3-E1 cells with very dense colonies after 28 days of induction medium exposure are seen in the given figure. In particular, on the flat substrates, the cells appeared more rounded than expected. This may be because, to avoid objects in the XRD results, only a mild fixative, ethanol, was used. The osteoblasts tended to have a larger μm micropatterned Si region of distribution, with various filopodia spreading from several of the cells. Biomineral clusters have also been found in cells, subclone 4, but not subclone 24, identical to previous studies, cells. More cells were shown to be detected on the 20 μm micropatterned Si tightly connected on the ridges than in the valleys.

The given picture depicts the evaluation of in vitro mineralization of PLAGA/n-HA scaffolds. In the first image, Alizarin red scaffold staining after 28 days of incubation in SBF or DDI water is shown: (a) PLAGA/n-HA in DDI water; (b) PLAGA scaffolding in DDI water; (c) PLAGA/n-HA in SBF; (d) PLAGA scaffolding in SBF. The graph illustrates the quantification, as a result of incubation time, of the calcium deposition from the surrounding SBF (*) signifies a slightly greater deposition of calcium at the same point of time than that of PLAGA scaffolds. (p =0.05).