Journal of Nanosciences: Pesquisa Atual

Ultrasound-Assisted Synthesis of Iron Oxide Nanoparticles: Application in Cytoxocity and Antibacterial Activity

Abstract

Sahar Qasim*, Mazin K Hamid and Mais E Ahmed

At the present time, the phenomenon of antibiotic resistance has increased by different species of bacteria. In this way, particularly in the situations of Metal Nanoparticles (MNPs) fabrication and MNPs surface modification, the emergence of nanotechnology as a new weapon has drawn increased attention. Currently, the safe way to manufacture nanoscales is at the lowest possible cost and the least harm to the environment of Fe₂O₃ NPs with novel shape through Ultrasound assisted. Ultraviolet Visible Spectrophotometer (UV-Vis), Energy Dispersive Xray spectroscopy (EDX), Scanning Electron Microscopy (SEM), Atomic Force Microscopic (AFM), X-ray Diffraction (XRD). These techniques were applied for physical characterization. Disc diffusion assay and Minimum Inhibitory Concentration (MIC) (16 μg/ml), were evaluated against gram negative (P. aeruginosa, Klebsiella spp.) and gram positive (S. aureus, S. pyogenes) Fe₂O₃ NPs with an average diameter size of 30 nm. Where the activity of iron nanoparticles prepared by a physical method showed a distinct activity against selected cancer cells.