Jornal Internacional de Saúde Pública e Segurança

Pneumocystis jirovecii in Chilean HIV Patients A Molecular Investigation

Abstract

Mariana Sowamber*

This study presents a molecular investigation of Pneumocystis jirovecii in Chilean HIV patients, aiming to provide insights into the genetic diversity, prevalence, and potential risk factors associated with Pneumocystis Pneumonia (PCP) in this specific population. P. jirovecii is a fungal pathogen known to cause severe respiratory infections, particularly in immunocompromised individuals. Through the analysis of genetic markers, the research explores the molecular epidemiology of P. jirovecii strains circulating among HIV-positive individuals in Chile. Additionally, the study investigates factors such as antiretroviral therapy status, CD4 cell count, and demographic variables to identify potential correlations with PCP prevalence. The findings contribute to a better understanding of the molecular characteristics of P. jirovecii in the context of HIV infection in Chile, aiding in the development of targeted prevention and treatment strategies.