Jornal de Trauma e Tratamento

Unveiling the Mind-Gut Connection: Psychiatric Disorders and the Microbiome

Abstract

Praveen Iyer* and Navanitha Thomas

The growing understanding of the gut microbiome's influence on human health has expanded beyond traditional realms of digestion and immunity. Recent research has shed light on a fascinating and intricate relationship between the gut microbiome and psychiatric disorders, revealing the existence of a mind-gut connection. This abstract explores the emerging evidence and mechanisms underlying this connection, emphasizing the bidirectional communication between the gut and the brain, and its impact on psychiatric disorders such as anxiety, depression, and even neurodevelopmental conditions. Through various studies, including animal models, clinical trials, and human microbiome sequencing, researchers have identified microbial signatures associated with psychiatric disorders, providing potential targets for therapeutic interventions. Furthermore, the abstract highlights the complex interplay of factors influencing the mind-gut connection, including diet, stress, immune system interactions, and the production of neuroactive compounds by gut microbes. Overall, this abstract aims to deepen our understanding of the intricate relationship between the gut microbiome and psychiatric disorders, ultimately paving the way for innovative approaches in the diagnosis, treatment, and prevention of these debilitating conditions.