Jornal de Citologia e Histologia

Thyroid nodules: Cytopathological correlations with the update Bethesda system 2017: our experience and a systematic review.

Abstract

Taha MM Hassan, Ahmed M.S. Hegazy, Mohammed M. Mosaed, , Nashwa Alzahrani, Abdalla Taher El-Enizi

Thyroid nodules (TNs) consider alarming problem among women. Although benign nodules far outnumber cancerous one. The risk of malignancy can be evaluated preoperatively using fine needle aspiration cytology (FNAC) under ultrasonographic guidance is widely used. The Bethesda system for Reporting Thyroid Cytopathology (TBSRTC) was worldwide accepted as standardized approach for cytological interpretation of these nodules. The purposes of this study are to apply and determine the risk of malignancy (ROM) of each standard cytological category of TBSRTC correlating with histopathological examinations and other publications. This study was performed on 1500 patients were complaining of thyroid nodules. All patients underwent for FNAC under ultrasonographic guidance. The obtained materials were diagnosed and categorized according the standard cytological categories of TBSRTC 2017. The cases which were diagnosed C4,C5, and C6 underwent to thyroid surgery, then all the taken specimens were examined and evaluated microscopically. The ROM in FNAC and a correlation with the histopathological findings were done.

Conclusion: Cytological interpretation of thyroid nodules applying the standard categories of the Bethesda system can minimize the risk of over surgical treatment and yielding more accurate approach for patient's management.