Jornal de Citologia e Histologia

Myeloid Sarcoma of Orbit in a Case of Acute Myeloid Leukemia

Abstract

Purva Patil, Bhavana Madhukar Bharambe, Rachana S Binayke and D’Costa Grace

Background: Extramedullary proliferation of cells of myeloid origin is termed as myeloid sarcoma. About 3-8% cases of AML present with myeloid sarcoma. Methods: A 10 year old child with proptosis was investigated and found to have mass in left supralateral region of left orbit. Enucleation of the eye was done and sent for histopathology along with the mass. Results: Histopathology showed sheets of round tumor cells positive for CD 43, LCA and C- Kit. Peripheral smear examination showed >20% blasts. Conclusion: A diagnosis of granulocytic sarcoma in a case of acute myelogenous leukemia was given.