Jornal de Citologia e Histologia

Morphological Study of Teeth and Periodontal Structures after Extraction in Syrian Hamster

Abstract

Ahmad Mohammad Khattab* and Hikmat Yakub

Background: Syrian Hamsters are considered a prime animal model to conduct histological examination in the oral cavity, having an exceptional ability to constantly regenerate their incisors. Syrian hamsters were also commonly used in experimentally induced cancerous growth studies.

Methods: 28 Syrian Hamsters have been distributed into six main groups in addition to control group. The animals of the control group have been sacrificed to get the normal morphological structure of the teeth and the periodontal structures. While the control group of animals have been sacrificed gradually, in order to study the stages of the restorative process, after the days that followed the extraction process.

Results: This research illustrates the morphology of the teeth in Syrian hamsters, mainly describing the depression area in the medial part of the root. It confirmed the presence of periodontal ligament tissue around these teeth. This Study confirmed in detail and with microscopic images the phases of the restorative process from the beginning of forming and organizing the thrombus till its Differentiation into the different dental and periodontal tissues.

Conclusions: The most significant achievement of this research its ability to detect focal regions of active cells which are able to differentiate into animal, dentin, and other different tissues.