Jornal de Filogenética e Biologia Evolutiva

Microbial Cell Factories: Harnessing Biodiversity for Pathway Construction, Robustness and Industrial Applicability

Abstract

Colin Friedman

Microbial cell factories represent a revolutionary approach to industrial biotechnology, leveraging the diversity of microorganisms to construct metabolic pathways for the production of valuable compounds. Biodiversity forms the cornerstone of this field, providing a vast reservoir of genetic material for pathway construction. However, the challenge lies not only in accessing this biodiversity but also in engineering robust microbial hosts capable of efficiently carrying out desired metabolic processes. In this article, we delve into the intersection of biodiversity, pathway construction, robustness, and industrial applicability in microbial cell factories.