Biologia Molecular: Acesso Aberto

Insights into Mitochondrial Metabolism and its Role in Aging and Age-related Diseases

Abstract

Paulina Zhang

Mitochondria are essential organelles responsible for energy production, regulation of cellular metabolism, and maintenance of cellular homeostasis. Their function is intricately linked to aging and the development of age-related diseases. This review delves into the molecular mechanisms of mitochondrial metabolism, emphasizing its role in aging and associated pathologies such as neurodegenerative diseases, cardiovascular disorders, and metabolic syndromes. Understanding mitochondrial metabolism provides critical insights into the aging process and highlights potential therapeutic targets for mitigating age-related diseases.