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Influence of IL-1β on Pain and Inflammatory Response after Placement of a Cement-screw-retained Restoration

Abstract

Florian Schedle

Interleukin-1β (IL-1β) is a key cytokine involved in inflammatory processes and pain modulation. Its role in the context of dental procedures, particularly after placement of cement–screw-retained restorations, is gaining attention. This article aims to explore the quantification and influence of IL-1β on pain and inflammatory response post-placement of cement–screw-retained restorations. We discuss the mechanism of action of IL-1β, its association with pain perception and inflammation, and its implications for dental practice. Additionally, we review recent studies investigating IL-1β levels in patients undergoing cement–screw-retained restoration procedures and their correlation with postoperative pain and inflammation. Understanding the role of IL-1β in this context can provide insights into optimizing patient care and improving treatment outcomes.

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