Imunoquímica e Imunopatologia

Dengue Diagnosis: Challenges and Opportunities

Abstract

Rohit Pawar and Vandana Patravale

An arthropod borne dengue viral infection is caused by dengue virus that gains entry into the human body via mosquito bites. Since dengue is a viral disease, there is no definitive drug or vaccine that can treat it, though research is going on around the world. As per the World Health Organization’s estimation, nearly 2.5 billion people around the globe are at risk of this infection. In resource-limited settings, these risks are compounded by inadequate or absent diagnostic methods. With a rapid upsurge and reemergence of dengue fever and other deadly diseases, especially in undeveloped regions, a key point in avoiding the high mortality rate and reducing disease burden is diagnosing the disease at its initial stages with the help of robust, cheap and sustainable diagnostics. Complications of dengue can be well prevented with early detection followed by accurate diagnosis. This review focus on challenges, opportunities and future prospects associated with dengue infection diagnosis.