Jornal de Citologia e Histologia

Cytological Confirmation of HPV 13 in Lesional Mucosa

Abstract

Xiangwei Xiao*

The most common causes of the unusual oral mucosa growth disorder known as focal epithelial hyperplasia (FEH) are the HPV strains 13 and 32. Eskimo and Native American children who live in North, South, or Central America are disproportionately affected. Over 90% of patients have HPV, particularly genotypes 13 and 32. Multiple, asymptomatic, 1 to 10 mm flat-topped, verrucous papules that range in colour from white to the neighbouring mucosa are a common presentation. They typically appear on the tongue, lips, gingiva, and oral mucosa. On rare occasions, several distinct papules will combine to produce a bigger lesion that resembles cobblestones. Condyloma is one of the same differential diagnoses for the oral cavity because of the variety in FEH.