Jornal de ciência e engenharia de tecidos

Cardiac Precision: Leveraging Human Stem Cells for Disease Modeling

Abstract

Victoria Hannah

Cardiac precision medicine necessitates accurate disease modeling for effective therapeutic development. Leveraging human stem cells, particularly induced pluripotent stem cells (iPSCs), offers a promising avenue for recapitulating cardiac diseases in vitro. This review explores the current advancements, challenges and future prospects of utilizing iPSC-derived cardiomyocytes for disease modeling, highlighting their potential in elucidating disease mechanisms, screening drug candidates and personalizing treatment strategies.