Shinsaku Kanazawa and Makoto Kammori*
Various immune-mediated disorders are associated with an increased risk of malignancy. Behçet’s disease (BD) is chronic, relapsing, systemic vasculitis of unknown etiology. It is characterized by recurrent urogenital aphthae and systemic manifestations, including ocular disease, skin lesions, gastrointestinal involvement, mammary manifestations, vascular disease, and arthritis. BD has been associated with malignancy in a few case series and case reports. However, the relationship between Behçet’s disease (BD) and breast cancer remains unclear. Here, we consider the relationship between BD and breast cancer through analysis of the medical literature and a review of our own experience.
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