Danish Jahan, Wajeeha Begum, Mariyam Roqaiya, Yousuf Khalil Hussaini
Background: Menorrhagia i.e., excessive menstrual blood loss is a common problem that interferes with women’s physical, emotional, social and material quality of life. Unani physicians have mentioned so many herbal formulations to treat menorrhagia. This study was aimed to compare the efficacy of polyherbal unani formulation and tranexamic acid on menorrhagia. Materials & Methods: This prospective randomized single blind standard controlled trial was conducted in Department of Niswan wa Qabala, National Institute of Unani Medicine. 40 patients were assigned to test (20) and control (20) groups. Both the test as well as control was given orally for five days from first day of menstrual cycle for two consecutive cycles. Assessment of efficacy was based on pictorial blood loss assessment chart (PBAC) to assess the amount of blood loss. Hb% and quality of life were also assessed as secondary outcome. Chi-square/ Fisher Exact test has been used to find the significance of study parameters on categorical scale between groups. Results: There was no significant difference found between the groups on all parameters assessed which shows that the test drug can be an alternative for tranexamic acid after clinical trial on large sample size and for longer duration. Conclusion: Test drug has been found having equal effect with tranexamic acid. There is need for further study on large sample size.
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