Ciência e terapia do câncer

Video-assisted Thoracoscopic Lobectomy in a Patient with Congenital Factor XI Deficiency

Abstract

Keigo Ozono, Takashi Nakaike, Daisuke Himeji, Sayaka Moriguchi, Kousuke Marutsuka, Kiichiro Beppu and Masafumi Nakamura

Congenital factor XI deficiency, called hemophilia C, is an autosomal recessive disorder. Bleeding complications are observed in 9.6% of surgeries on such patients. Herein, we presented the first report of a case of lung cancer with FXI deficiency. The patient safely underwent video-assisted thoracoscopic lobectomy after replenishment of coagulation factors via preoperative fresh frozen plasma transfusions prior to surgery.