Medicina Nuclear e Radioterapia

Superscan Imaging on Ga-68 PSMA PET/CT in Prostate Cancer Patient

Abstract

Sait Sager, Elife Akgun, Onur Erdem Şahin, Burak Akgun and Kerim Sonmezoglu

Prostate cancer (PCa) is the most frequent tumor in men worldwide. PCa bone metastasis is mainly osteosclerotic, and is caused by a relative excess of osteoblast activity. A superscan on Tc-99m bone scintigraphy is described in multiple skeletal metastatic disease. Prostate-specific membrane antigen (PSMA) is a cell surface protein with high expression in prostate carcinoma cells. Ga-68 labelled PSMA imaging is used for staging and to evaluate the most appropriate therapy.