Journal of Integrative Oncology

Paraneoplastic Hepatic Dysfunction with Jaundice in a Case of Primary Renal Synovial Sarcoma: A very Rare Scenario

Abstract

Sudheer Dewana, Kalpesh Parmar, Gopal Sharma, Amit Bansal, Pankaj Panwar and Ravimohan S Mavuduru

Nonmetastatic hepatic dysfunction known as Stauffer’s syndrome is a rare entity. It is commonly associated with clear cell carcinoma of the kidney. Rarely it has been reported in cases of prostatic carcinoma, bronchogenic tumor, and lymphoproliferative diseases. Stauffer’s syndrome presents an elevated alkaline phosphatase, aminotransferases, and prolonged prothrombin time without jaundice. However, a very rare variant of Stauffer’s syndrome presenting with jaundice has been reported in few case reports of clear cell carcinoma of the kidney. But such a presentation in cases of renal sarcomas has not been reported so far. Here we report a unique case of primary synovial sarcoma of kidney presenting as nonmetastatic cholestatic jaundice.