Jornal de Histologia Molecular e Fisiologia Médica

Origins, Mechanisms and Impacts of Choroidal Neovascular Membranes in Retinal and Choroidal Tumors

Abstract

Ivan Petrov

Choroidal Neovascular Membranes (CNVMs) are a significant concern in the context of retinal and choroidal tumors. This article explores the origins, mechanisms, and impacts of CNVMs in such tumors. Beginning with an introduction to CNVMs and their clinical significance, the literature review delves into the various factors contributing to CNVM development and progression. Discussions focus on the intricate mechanisms underlying CNVM formation, including angiogenesis, Vascular Endothelial Growth Factor (VEGF) signaling, and immune system involvement. Furthermore, the article addresses the impacts of CNVMs on visual function, tumor growth, and treatment outcomes. Finally, the conclusion synthesizes key findings and outlines potential avenues for future research to better understand and manage CNVMs in retinal and choroidal tumors.