Ciência e terapia do câncer

MicroRNA: A New Promising Biomarker

Abstract

Rao VD

Understanding the molecular basis of life is at the center today, however, advances in the field of Molecular
Biology and genomics improved the compassionate of the genetic basis of diseases in human. There is an
increased interest in the function of non-coding RNA transcripts in early diagnosis and treatment to various
diseases. MicroRNAs are classes of small non-coding RNAs that consist of 22-25 nucleotides, which are one of the
most current forms of molecular characterization of tumours. The target MicroRNA regulates the mRNA translation
that causes the subsequent decrease in the protein expression. This paper aims to review some of the accumulated
literature that has proven that miRNAs are strong biomarkers in diagnosis and treatment of life threatening diseases
such as cancer.