Ciência e terapia do câncer

Malignant Mesothelioma of Peritoneum: About a Case with Review of the Literature

Abstract

Berhil H, Chenna H, Nouni K, Mouhajir N, Tolba A, Zaidi H, Mezouri V, Hassouni K, Kebdani T, El gueddari BK and Benjaafar N

Malignant mesothelioma of the peritoneum is rather unusual and is only 10-20% of malignant mesothelioma. Malignant mesothelioma is pleural recognized by its location. The etiology of malignant mesothelioma is in 80% of cases prior contact with asbestos but there are cases without specific cause. The prognosis for MPM is poor with median survival of 5.4 months versus 12.5 months for pleural mesothelioma. The diagnosis of MPM is often difficult and requires surgical biopsies by laparoscopy or laparotomy or ascitic cytology. A surgical cytoreduction combined with hyperthermic intraperitoneal chemotherapy is the best therapeutic approach for MPM but unfortunately often advanced disease at diagnosis. We must therefore resort to systemic chemotherapy based on platinum or symptomatic treatments.