Medicina Nuclear e Radioterapia

Incidental Detection of Thyroid Neoplasm on ^99mTc-SestaMIBI Myocardial Perfusion Scan - A Novel Tumour Tracer Revisted

Abstract

Manjit Sarma, Padma Subramanyam and Palaniswamy Shanmuga Sundaram

We report a case of a young Indian male who had an incidental abnormal focal uptake of 99mTechnetium-MIBI (Methoxy Isobutyl Isonitrile) in the right lobe of thyroid while undergoing 99mTc-MIBI myocardial perfusion gated SPECT (Single Photon Emission Computed Tomography) imaging as a part of his myocardial ischemia status evaluation. This focal uptake was eventually detected to be a malignant thyroid nodule for which he underwent total thyroidectomy. His biopsy was reported as Hurthe cell nodule. Though incidental detection of thyroid, breast and lung malignant pathology on 99mTc- MIBI myocardial perfusion scans is well known, this case is a reminder and exemplifies the potential of 99mTc-MIBI not only as an excellent myocardial perfusion agent but also as a non specific tumour tracer (for its larger usage as a tracer for neoplastic survey).