Jornal de Vasculite

Impact of Environmental Factors on the Development and Progression of Vasculitis Current Evidence

Abstract

Amy Angela*

Vasculitis encompasses a heterogeneous group of autoimmune disorders characterized by inflammation of blood vessels. While genetic predisposition is well-established in vasculitis, emerging evidence suggests a significant influence of environmental factors on disease development and progression. This article provides a comprehensive review of the current evidence linking various environmental factors, including infectious agents, pollutants, medications, and lifestyle factors, to vasculitis. Understanding the interplay between genetic susceptibility and environmental triggers is essential for elucidating the complex pathogenesis of vasculitis. Moreover, recognizing modifiable environmental factors holds promise for preventive strategies and targeted interventions to mitigate disease burden. Through an exploration of recent research findings and clinical observations, this article aims to enhance awareness among healthcare professionals regarding the role of environmental influences in vasculitis, ultimately guiding personalized approaches to patient care and management.