Clinical and Medical Case Reports

Glucose Profile and HbA1c using Continuous Glucose Monitoring (CGM): Case Report

Abstract

Hiroshi Bando, Koji Ebe , Yoshikane Kato , Setsuko Kanazawa , Mayumi Tanaka , Etsuko Sueki , Hiroe Kanagawa , Takafumi Kawata , Atsuko Kawahito , Masahiro Bando and Yoshikazu Yonei

Background: Continuous Glucose Monitoring (CGM) has been in focus for treatment of diabetes. Recently, a sensor-based flash glucose monitoring system, FreeStyle Libre (Abbott), has been introduced to clinical practice.
Case and results: The patient was 53 year-old female with type 1 diabetes mellitus (T1DM), who showed BMI 25.1 kg/m², HbA1c 9.5% in January, 6.0% in June and 7.7% in November, 2017 as data on outclinic. CGM measured glucose every 15 minutes in 24 hours for 14 days on June and November, and estimated HbA1c was 5.4% and 6.1%, respectively with discrepancy.
Discussion and conclusion: The beneficial points of FreeStyle Libre have been accurate, convenient and small size for clinical use for lessen hypoglycemia episodes. Key benefits of CGM monitoring are frequency of testing, trends, alarms, therapy optimization. Former studies for FreeStyle Libre tended to show lower values and larger mean absolute relative difference (MARD) in lower range of glucose levels, suggesting possible cause of the discrepancy for HbA1c levels. FreeStyle Libre for CGM would lead to better balance optimization of glucose control and current results would become basal data for future investigation of CGM.