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Fatal Sepsis and Multiorgan Failure Following Bacillus Calmette-Guerin Instillation for Bladder Cancer Treatment

Abstract

Carlo Moreschi and Ugo Da Broi

A Fatal sepsis and multiple organ failure occurred in a 61-year-old man, seven days after the anti-tumoral instillation of bacillus Calmette-Guérin for bladder carcinoma treatment. Autopsy findings revealed uncommon diffuse miliary caseating granulomas involving lungs. Judicial Authority censured the urology surgical team for delayed diagnosis and incorrect therapeutical intervention, not applied when early local and systemic adverse effects arose, in absence of exhaustive information given to the patient on all post-operative complications.