Jornal de Agentes Antimicrobianos

Efficacy of Crude Leaf Extracts of Aloe secundiflora on Selected Enteric Bacterial Pathogens and Candida albicans

Abstract

Rachuonyo HO, Ogola PE, Arika WM and Wambani JR

The main aim of the study was to determine the antimicrobial effect of methanolic leaf extract of Aloe secundiflora against four Gram-negative bacteria (Shigella flexineri, Salmonella typhi, Escherichia coli and Enterococcus faecalis), one Gram-positive bacteria (Staphylococcus aureus) and on one fungal pathogen (Candida albicans) by Kirby Bauer method. The extract was found to be more effective against all the bacterial pathogens and Candida albicans using ciprofloxacin as the standard antibiotic for Gram-negative bacterial pathogens, Vancomycin for Staphylococcus aureus and Fluconazole for Candida albicans with an MIC range of 3-11 mg/ml. the preliminary analysis for the extracts confirmed the presence of alkaloids, saponins, tannins and flavonoids. Our study revealed that, the extract from Aloe secundiflora leaf can be used in treating the diseases caused by the bacterial pathogens.