Jornal de AIDS e Pesquisa Clínica

Central Nervous System Antiretroviral High Penetration Therapy

Abstract

Francisco Tomaz Meneses de Oliveira, Guilherme Sciascia do Olival and Augusto Cesar Penalva de Oliveira

The use of highly effective antiretroviral therapy penetration into the central nervous system has indicators for input that can eradicate the viral load in cerebrospinal fluid, thereby helping to prevent the virus compartmentalization in CNS and hence probably preventing perpetuation of these cognitive disorders associated with HIV virus. However, more studies are necessary in order to demonstrate the real pathophysiological mechanisms associated with these effects and to prove that the side effects associated with the use of these medications are harmless than the benefits achieved on the neurocognitive disorders.