Darren Frost
Autoimmunity in patients with inborn errors of immunity (IEI) represents a complex clinical phenomenon characterized by dysregulated immune responses that lead to autoimmune manifestations. This case series examines the clinical presentation, immunological features, and management strategies in patients with IEI who develop autoimmune disorders. Insights from these cases highlight the diverse spectrum of autoimmune diseases observed in IEI, ranging from systemic lupus erythematosus to autoimmune cytopenias and vasculitis. Understanding the underlying immunopathogenesis and genetic predispositions in these patients is crucial for optimizing diagnostic approaches and therapeutic interventions tailored to individualized immune profiles.
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