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Anti-diabetic Activity of Synthetic Aryltetalin Derivatives

Abstract

M. Chaitramallu, G. R. Parvathi, Devaraju Kesagodu and Ranjini

The aryltetralin derivatives were extracted from plant and also synthesized using tetralone as a starting material. They were synthesized by replacing 1,3-methylene dioxy ring with dimethoxy, hydroxy, methyl, chlorine, hydrogen and methoxy group. The structure of the final compounds was confirmed by 1H NMR, 13C NMR, mass spectra and elemental analysis data and the analogues were screened for anti-diabetic activity. It is noteworthy all the synthesized derivatives exhibits good anti-diabetic activity with respect to extracted aryltetralin compound.

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