Medicina Nuclear e Radioterapia

A Case Report of Retroperitoneal Seminoma and Literature Review

Abstract

Chiumento Costanza, Fiorentino Alba, Tartarone Alfredo, Lapadula Loredana, Caivano Rocchina, Cozzolino Mariella and Vincenzo Fusco

Aims and background: Extra-gonadal germ cell tumours (EGCT) are rare tumors, which usually occur in the mediastinum or retroperitoneum; in particular, primary retroperitoneal seminomas account for approximately 2% of all seminomas. We report the case of a 34-year-old male with a locally advanced retroperitonal seminoma.
Methods: The patient underwent debulking surgery followed by cisplatin-based chemotherapy and radiotherapy. Results: No evidence of recurrence was detected during a 30 months follow-up. Although retroperitoneal seminoma is rare, this entity should be considered in the differential diagnosis of a male patient presenting with a mass in the retroperitoneum.
Conclusions: Our case, according to data reported in literature, confirms the curability of retroperitoneal seminoma even in presence of bulky disease, and it represents an example of revised treatment procedure due to patient’s particular condition.